Thermo Scientific HyPerforma 5:1 Single-Use Bioreactor – 250L, Jacketed, Scalable, Brand New

The HyPerforma 250L Single-Use Bioreactor (S.U.B.) is a GMP-ready, stirred-tank bioreactor system designed to deliver maximum flexibility and scalability for biologics production. Built with a 5:1 turndown ratio, this bioreactor allows operation from 50L to 250L volumes, minimizing seed transfers and reducing disposable use.

This unit features a jacketed stainless-steel tank, magnetically coupled agitation, and compatibility with open-architecture or turnkey control systems (e.g., DeltaV, Allen-Bradley, Siemens). It includes ports for multiple probes, dual gas spargers (cross-flow and drilled-hole), and optional accessories for enhanced process control.

Specifications

• Model: HyPerforma 250L Single-Use Bioreactor
  
• Rated Working Volume: 250 L
  
• Minimum Working Volume: 50 L
  
• Total Volume (liquid + gas): 316 L
  
• Turndown Ratio: 5:1
  
• Impeller: 1 × 3-blade, 20 cm diameter, 45° pitch
  
• Mixing Speed: 30–150 rpm
  
• Mixing Flow: Down-pumping
  
• Drive Motor: 208V AC, 3-phase, 0.25 hp
  
• Tank Jacket Area: 1.3 m² (cooling/heating)
  
• Jacket Flow Rate: 136 L/min @ 3.4 bar
  
• Heat-up Time (5°C–37°C): 1.1 hr (20% vol), 3.4 hr (100% vol)
  
• Overall Dimensions (W × L × H): 121.3 × 121.3 × 214.9 cm
  
• Control Type: External (not included, shared with Unit #145)
  
• Probe Ports: 4 (12 mm Ø × 215–235 mm insertion)
  
• Load Cells: Included
  
• Status: Brand New, Unopened
  
• Year: 2024
  
• Location: Taiwan

Key Features

• 5:1 turndown ratio reduces BPC usage and seed steps
  
• Open architecture for compatibility with various controllers
  
• Jacketed tank for rapid thermal control
  
• Pre-configured for dual spargers for seed and process culture
  
• Load cells and probe-ready ports included
  
• Shared controller with Unit #145 (controller not included)

Applications
Perfect for vaccine production, cell therapies, and large-scale upstream bioprocessing. Ideal for facilities requiring flexibility, sterility, and scalability across R&D to clinical or GMP-grade production.

Condition
Brand new, factory-sealed. Ready for integration. Shares external controller with another unit (#145). Accessories and controller not included.